DENND1B 抗体 (AA 39-68)
Our Local Distributor
北京 101111
Quick Overview for DENND1B 抗体 (AA 39-68) (ABIN7874606)
抗原
See all DENND1B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 39-68
-
原理
- DENND1B Antibody
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the DENND1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the DENND1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
-
别名
- DENND1B
-
背景
- Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
-
UniProt
- Q6P3S1
抗原
-