MMP10 抗体 (AA 380-410)
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Quick Overview for MMP10 抗体 (AA 380-410) (ABIN7874520)
抗原
See all MMP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 380-410
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原理
- MMP10 Antibody| Matrix metalloproteinase 10
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免疫原
- A portion of amino acids 380-410 from the human protein was used as the immunogen for the MMP10 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MMP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the MMP10 antibody at -20oC.
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- MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))
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别名
- MMP10
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背景
- MMP10 belongs to the matrix metalloproteinase family, a group of enzymes that play a key role in tissue remodeling by degrading various components of the extracellular matrix. Specifically, MMP10 is known for its ability to degrade collagen, a major structural component of connective tissue. By breaking down collagen, MMP10 helps to facilitate the turnover of damaged tissues and promote the regeneration of new, healthy tissue. One of the most intriguing aspects of MMP10 is its regulation in response to different stimuli. For example, MMP10 expression can be induced by factors such as growth factors, cytokines, and mechanical stress. This dynamic regulation allows MMP10 to respond to changing environmental conditions and play a crucial role in processes such as tissue repair and inflammation. Research has also shown that dysregulation of MMP10 activity can have detrimental effects on tissue homeostasis. For example, overexpression of MMP10 has been linked to various pathological conditions, including cancer metastasis and inflammatory diseases. On the other hand, decreased MMP10 activity has been associated with impaired wound healing and fibrosis.
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UniProt
- P09238
抗原
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