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MMP10 抗体 (AA 380-410)

The 小鼠 多克隆 anti-MMP10 antibody is suitable to detect MMP10 in samples from 人. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN7874520
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MMP10 抗体 (AA 380-410) (ABIN7874520)

抗原

See all MMP10 抗体
MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

适用

  • 69
  • 24
  • 10
  • 2
  • 1

宿主

  • 67
  • 9
小鼠

克隆类型

  • 69
  • 7
多克隆

标记

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  • 2
  • 2
  • 1
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This MMP10 antibody is un-conjugated

应用范围

  • 53
  • 34
  • 29
  • 15
  • 10
  • 9
  • 6
  • 4
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 14
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    • 3
    • 2
    • 2
    • 1
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    • 1
    • 1
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    AA 380-410

    原理

    MMP10 Antibody| Matrix metalloproteinase 10

    免疫原

    A portion of amino acids 380-410 from the human protein was used as the immunogen for the MMP10 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the MMP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the MMP10 antibody at -20oC.
  • 抗原

    MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

    别名

    MMP10

    背景

    MMP10 belongs to the matrix metalloproteinase family, a group of enzymes that play a key role in tissue remodeling by degrading various components of the extracellular matrix. Specifically, MMP10 is known for its ability to degrade collagen, a major structural component of connective tissue. By breaking down collagen, MMP10 helps to facilitate the turnover of damaged tissues and promote the regeneration of new, healthy tissue. One of the most intriguing aspects of MMP10 is its regulation in response to different stimuli. For example, MMP10 expression can be induced by factors such as growth factors, cytokines, and mechanical stress. This dynamic regulation allows MMP10 to respond to changing environmental conditions and play a crucial role in processes such as tissue repair and inflammation. Research has also shown that dysregulation of MMP10 activity can have detrimental effects on tissue homeostasis. For example, overexpression of MMP10 has been linked to various pathological conditions, including cancer metastasis and inflammatory diseases. On the other hand, decreased MMP10 activity has been associated with impaired wound healing and fibrosis.

    UniProt

    P09238
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