FTL 抗体 (Light Chain)
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北京 101111
Quick Overview for FTL 抗体 (Light Chain) (ABIN7874496)
抗原
See all FTL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 38-165, Light Chain
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原理
- FTL Antibody / Ferritin Light Chain
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 38-165 from the human protein was used as the immunogen for the FTL antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the FTL antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the FTL antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- FTL (Ferritin, Light Polypeptide (FTL))
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别名
- FTL
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背景
- Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyper-ferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
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UniProt
- P02792
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途径
- Transition Metal Ion Homeostasis
抗原
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