HTR2C 抗体 (AA 372-458)
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Quick Overview for HTR2C 抗体 (AA 372-458) (ABIN7874430)
抗原
See all HTR2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 372-458
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原理
- 5-HT2C Receptor Antibody / HTR2C
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids N372-V458) was used as the immunogen for the 5-HT2C Receptor antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the 5-HT2C Receptor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the 5-HT2C Receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
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别名
- 5-HT2C Receptor
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背景
- This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.
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UniProt
- P28335
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
抗原
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