PDP 抗体 (AA 37-537)
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Quick Overview for PDP 抗体 (AA 37-537) (ABIN7874408)
抗原
See all PDP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 37-537
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原理
- PDP1 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S37-E537) was used as the immunogen for the PDP1 antibody.
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 308-336) antibody
PDP 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31327 unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) antibodyKO Validated PDP 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) antibodyPDP 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 1-154) antibodyPDP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 72-260) antibodyPDP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 37-537) antibodyPDP 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 315-537) antibodyPDP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 366-395), (Middle Region) antibodyPDP 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Phosphatase (PDP) (AA 821-850), (C-Term) antibodyPDP 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PDP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PDP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDP (Pyruvate Dehydrogenase Phosphatase (PDP))
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别名
- PDP1
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背景
- Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported, one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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UniProt
- Q9P0J1
抗原
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