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Plakophilin 2 抗体 (AA 369-804)

This 兔 多克隆 antibody specifically detects Plakophilin 2 in WB, ELISA, IHC (p) 和 FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN7874381
发货至: 中国
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Quick Overview for Plakophilin 2 抗体 (AA 369-804) (ABIN7874381)

抗原

See all Plakophilin 2 (PKP2) 抗体
Plakophilin 2 (PKP2)

适用

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人, 大鼠, 小鼠

宿主

  • 41
  • 4
  • 2
  • 1

克隆类型

  • 44
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多克隆

标记

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This Plakophilin 2 antibody is un-conjugated

应用范围

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  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 11
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    • 2
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    • 1
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    AA 369-804

    原理

    Plakophilin 2 Antibody / PKP2

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived human recombinant protein (amino acids R369-Q804) was used as the immunogen for the Plakophilin 2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Plakophilin 2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Plakophilin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Plakophilin 2 (PKP2)

    别名

    Plakophilin 2

    背景

    Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene may regulate the signaling activity of beta-catenin and is required to maintain transcription of genes that control intracellular calcium cycling including ryanodine receptor 2, ankyrin-B, triadin, and calcium channel, voltage-dependent, L type, alpha 1C. Mutations in this gene are associated with different inherited cardiac conditions including Arrythmogenic Cardiomyopathy, Brugada Syndrome, and Idiopathic Ventricular Fibrillation. A processed pseudogene with high similarity to this gene has been mapped to chromosome 12p13.

    UniProt

    Q99959

    途径

    Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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