PDE12 抗体 (AA 36-607)
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Quick Overview for PDE12 抗体 (AA 36-607) (ABIN7874325)
抗原
See all PDE12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 36-607
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原理
- PDE12 Antibody / Mitochondrial deadenylase / 2',5'-phosphodiesterase 12
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids E36-K607) was used as the immunogen for the PDE12 antibody.
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亚型
- IgG
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anti-Phosphodiesterase 12 (PDE12) (AA 17-300) antibody
PDE12 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 362-390), (C-Term) antibodyPDE12 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB27765 unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 1-575) antibodyPDE12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 559-609) antibodyPDE12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (C-Term) antibodyPDE12 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔, 猴, Pig, Bat, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 290-602) antibodyPDE12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 369-398), (C-Term) antibodyPDE12 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PDE12 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PDE12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDE12 (Phosphodiesterase 12 (PDE12))
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别名
- PDE12
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背景
- PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
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UniProt
- Q6L8Q7
抗原
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