NUP214 抗体 (AA 36-374)
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Quick Overview for NUP214 抗体 (AA 36-374) (ABIN7874312)
抗原
See all NUP214 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 36-374
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原理
- NUP214 Antibody / Nucleoporin 214
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids K36-E374) was used as the immunogen for the NUP214 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NUP214 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NUP214 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NUP214 (Nucleoporin 214kDa (NUP214))
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别名
- NUP214
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背景
- Nucleoporin 214 (Nup2014) is a protein that in humans is encoded by the NUP214 gene. The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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UniProt
- P35658
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途径
- Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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