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Angiopoietin 2 抗体 (AA 357-404)

This 兔 多克隆 antibody specifically detects Angiopoietin 2 in WB, ELISA, IF, IHC (p) 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7874276
发货至: 中国
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Quick Overview for Angiopoietin 2 抗体 (AA 357-404) (ABIN7874276)

抗原

See all Angiopoietin 2 (ANGPT2) 抗体
Angiopoietin 2 (ANGPT2)

适用

  • 95
  • 56
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  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 11
  • 9
  • 2
  • 1

克隆类型

  • 70
  • 49
多克隆

标记

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  • 13
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
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This Angiopoietin 2 antibody is un-conjugated

应用范围

  • 83
  • 54
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  • 4
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 15
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    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
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    AA 357-404

    原理

    ANGPT2 Antibody / Angiopoietin-2 / ANG2

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids N357-K404) was used as the immunogen for the ANGPT2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ANGPT2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the ANGPT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Angiopoietin 2 (ANGPT2)

    别名

    ANGPT2

    背景

    ANGPT2, also known as ANG2 or Angiopoietin 2, is a protein that in humans is encoded by the ANGPT2 gene. It is mapped to 8p23.1. ANGPT2 is a naturally occurring antagonist of ANG1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis. The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema, tracheal. ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema. It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema.

    UniProt

    O15123

    途径

    RTK signaling
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