MSH6 抗体 (AA 357-388)
Our Local Distributor
北京 101111
Quick Overview for MSH6 抗体 (AA 357-388) (ABIN7874275)
抗原
See all MSH6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 357-388
-
原理
- MSH6 Antibody
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids D357-H388) was used as the immunogen for the MSH6 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the MSH6 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the MSH6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
-
别名
- MSH6
-
背景
- MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
-
UniProt
- P52701
-
途径
- DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
抗原
-