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KRT14 抗体 (AA 351-472)

This 小鼠 单克隆 antibody specifically detects KRT14 in FACS 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7874234
发货至: 中国
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Quick Overview for KRT14 抗体 (AA 351-472) (ABIN7874234)

抗原

See all KRT14 抗体
KRT14 (Keratin 14 (KRT14))

适用

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人, 小鼠, 大鼠

宿主

  • 145
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  • 2
小鼠

克隆类型

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  • 1
单克隆

标记

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This KRT14 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

KRT14-2375
  • 抗原表位

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    AA 351-472

    原理

    Cytokeratin 14 Antibody / KRT14 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 351-472) was used as the immunogen for this Cytokeratin 14 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the Cytokeratin 14 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Cytokeratin 14 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    KRT14 (Keratin 14 (KRT14))

    别名

    Cytokeratin 14

    背景

    Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

    UniProt

    P02533
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