Recombinant KRT14 抗体 (AA 350-472)
Our Local Distributor
北京 101111
Quick Overview for Recombinant KRT14 抗体 (AA 350-472) (ABIN7874197)
抗原
See all KRT14 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- AA 350-472
-
原理
- Recombinant Cytokeratin 14 Antibody (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- A recombinant human KRT14 fragment (within amino acids 350-472) was used as the immunogen for the recombinant Cytokeratin 14 antibody.
-
亚型
- IgG, kappa
-
-
anti-Keratin 14 (KRT14) antibody
KRT14 适用: 人 IHC, WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, 小鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (AA 1-484) antibodyKRT14 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal LL002 unconjugated
anti-Keratin 14 (KRT14) (AA 351-472) antibodyKRT14 适用: 人, 大鼠, 小鼠, Pig IHC, FACS 宿主: 小鼠 Monoclonal KRT14-2375 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人, 大鼠, Pig, 犬 IHC, WB, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal RCK107 unconjugated
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 IHC, WB, FACS, ICC, IP 宿主: 小鼠 Monoclonal LL002 unconjugated Recombinant Antibody
anti-Keratin 14 (KRT14) (C-Term) antibodyKRT14 适用: 人 IHC, WB, FACS, ICC, IP 宿主: 小鼠 Monoclonal LL002 unconjugated Recombinant Antibody
anti-Keratin 14 (KRT14) antibodyKRT14 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
- Optimal dilution of the recombinant Cytokeratin 14 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the recombinant Cytokeratin 14 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- KRT14 (Keratin 14 (KRT14))
-
别名
- Cytokeratin 14
-
背景
- Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. It always pairs with the type II keratin K5 and form the primary keratin pair of the keratinocytes of stratified squamous epithelia, including the epidermis as well as mucosal non-keratinizing stratified squamous epithelia.Cytokeratin 14 is strongly expressed in the undifferentiated basal cell layer containing the stem cells and are down-regulated in the differentiating suprabasal cell layers. Otherwise, in the widely well stratified follicular outer root sheath, cytokeratin 14 is uniformly expressed throughout all layers. The expression spectrum of cytokeratin 14 in tumors corresponds well to the patterns in normal epithelia. Thus, most squamous cell carcinomas as well as malignant mesotheliomas strongly express this keratin whereas little, focal, or no expression is found in adenocarcinomas.Cytokeratin 14 may be a useful marker in the differential diagnosis of squamous cell carcinoma from other epithelial tumors. Recent studies also indicate that CK14 expression in breast cancer corresponded with poor clinical outcome and that CK14 may have diagnostic value in the sub-classification of NSCLC.
-
UniProt
- P02533
抗原
-
