FOXN1 抗体 (AA 350-378)
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Quick Overview for FOXN1 抗体 (AA 350-378) (ABIN7874182)
抗原
See all FOXN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-378
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原理
- FOXN1 Antibody / Forkhead box protein N1
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免疫原
- A portion of amino acids 350-378 from the human protein was used as the immunogen for this FOXN1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the FOXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4oC for up to one month. For long term, aliquot the FOXN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FOXN1 (Forkhead Box N1 (FOXN1))
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别名
- FOXN1
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背景
- FOXN1 is a member of the forkhead box (FOX) family of transcription factors, which play key roles in regulating gene expression. FOXN1 is primarily known for its critical function in the development and maintenance of the thymus, a crucial organ of the immune system. This protein is essential for the differentiation and maturation of thymic epithelial cells, which in turn support the development of T cells, a vital component of the adaptive immune response. Mutations in the FOXN1 gene have been linked to a rare genetic condition known as T-cell lymphopenia, where individuals have decreased levels of T cells and are more susceptible to infections. In addition to its role in immune function, FOXN1 has also been investigated for its potential in regenerative medicine. Studies have shown that FOXN1 expression is crucial for the regeneration of hair follicles and skin in mammals.
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UniProt
- O15353
抗原
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