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STK39 抗体 (AA 346-376)

The 兔 多克隆 anti-STK39 antibody (ABIN7874119) specifically detects STK39 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7874119
发货至: 中国
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Quick Overview for STK39 抗体 (AA 346-376) (ABIN7874119)

抗原

See all STK39 抗体
STK39 (serine threonine Kinase 39 (STK39))

适用

  • 93
  • 44
  • 20
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
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宿主

  • 93
  • 7
  • 1

克隆类型

  • 72
  • 29
多克隆

标记

  • 54
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
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This STK39 antibody is un-conjugated

应用范围

  • 80
  • 51
  • 44
  • 14
  • 10
  • 10
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 346-376

    原理

    SPAK Antibody / STK39

    纯化方法

    SAS precipitation

    免疫原

    A portion of amino acids 346-376 from the human protein were used as the immunogen for the SPAK antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the SPAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the SPAK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    STK39 (serine threonine Kinase 39 (STK39))

    别名

    SPAK

    背景

    SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas. SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SPAK. SPAK activates the p38 MAP kinase pathway in cotransfection assays. Full-length SPAK is expressed in the cytoplasm in transfected cells, while a mutant corresponding to caspase-cleaved STK39 localizes predominantly in the nucleus.

    UniProt

    Q9UEW8
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