STK39 抗体 (AA 346-376)
(4 references)-
- 抗原 See all STK39 抗体
- STK39 (serine threonine Kinase 39 (STK39))
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抗原表位
- AA 346-376
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STK39 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SPAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-376 amino acids from the Central region of human SPAK.
- 克隆位点
- RB03418
- 亚型
- Ig Fraction
- Top Product
- Discover our top product STK39 Primary Antibody
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anti-serine threonine Kinase 39 (STK39) antibody
STK39 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Internal Region) antibodyVerified STK39 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Ser325) antibodySTK39 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Ser311) antibodySTK39 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (AA 63-545) antibodySTK39 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (pSer311) antibodySTK39 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (pSer309) antibodySTK39 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) antibodySTK39 适用: 人 WB, IHC, IF, FACS 宿主: 小鼠 Monoclonal 4E3 unconjugated
anti-serine threonine Kinase 39 (STK39) (C-Term) antibodySTK39 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (pSer325) antibodySTK39 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy." in: PLoS ONE, Vol. 8, Issue 9, pp. e74614, (2013) (PubMed).
: "From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 1, pp. 226-31, (2009) (PubMed).
: "PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells." in: The Journal of biological chemistry, Vol. 283, Issue 32, pp. 22147-56, (2008) (PubMed).
: "Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function." in: The Journal of biological chemistry, Vol. 280, Issue 27, pp. 25491-8, (2005) (PubMed).
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: "STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy." in: PLoS ONE, Vol. 8, Issue 9, pp. e74614, (2013) (PubMed).
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- 抗原
- STK39 (serine threonine Kinase 39 (STK39))
- 别名
- SPAK (STK39 产品)
- 别名
- dcht antibody, pask antibody, spak antibody, MGC69537 antibody, DCHT antibody, PASK antibody, SPAK antibody, Spak antibody, AW227544 antibody, AW556857 antibody, RF005 antibody, Rnl5 antibody, serine/threonine kinase 39 antibody, serine/threonine kinase 39 L homeolog antibody, serine threonine kinase 39 antibody, stk39 antibody, STK39 antibody, stk39.L antibody, Stk39 antibody
- 背景
- SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas. SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SPAK. SPAK activates the p38 MAP kinase pathway in cotransfection assays. Full-length SPAK is expressed in the cytoplasm in transfected cells, while a mutant corresponding to caspase-cleaved STK39 localizes predominantly in the nucleus.
- 分子量
- 59474
- 基因ID
- 27347
- NCBI登录号
- NP_037365
- UniProt
- Q9UEW8
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