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RNLS 抗体 (AA 34-235)

The 小鼠 单克隆 anti-RNLS antibody is suitable to detect RNLS in samples from 人. It has been validated for ELISA.
产品编号 ABIN7874067
发货至: 中国
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Quick Overview for RNLS 抗体 (AA 34-235) (ABIN7874067)

抗原

See all RNLS 抗体
RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

适用

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宿主

  • 58
  • 22
  • 1
小鼠

克隆类型

  • 49
  • 32
单克隆

标记

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  • 1
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This RNLS antibody is un-conjugated

应用范围

  • 52
  • 32
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  • 10
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ELISA

克隆位点

RNLS-1940
  • 抗原表位

    • 15
    • 13
    • 9
    • 3
    • 2
    • 2
    • 1
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    AA 34-235

    原理

    Renalase Antibody

    纯化方法

    Protein G affinity

    免疫原

    A portion of amino acids 34-235 from the human protein was used as the immunogen for the Renalase antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Renalase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Renalase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

    别名

    Renalase

    背景

    Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

    UniProt

    Q5VYX0
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