PPID 抗体 (AA 336-370)
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北京 101111
Quick Overview for PPID 抗体 (AA 336-370) (ABIN7874049)
抗原
See all PPID 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 336-370
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原理
- Cyclophilin D Antibody / PPID
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 336-370 from the human protein was used as the immunogen for the Cyclophilin D antibody.
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亚型
- Ig Fraction
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anti-Peptidylprolyl Isomerase D (PPID) (AA 7-206) antibody
PPID 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase D (PPID) antibodyKD Validated PPID 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB1560 unconjugated Recombinant Antibody
anti-Peptidylprolyl Isomerase D (PPID) (AA 336-370) antibodyPPID 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB55961 unconjugated
anti-Peptidylprolyl Isomerase D (PPID) (AA 1-370) antibodyPPID 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase D (PPID) (AA 161-370) antibodyPPID 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase D (PPID) antibodyPPID 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase D (PPID) (AA 306-370) antibodyPPID 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidylprolyl Isomerase D (PPID) (AA 1-370) antibodyPPID 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Peptidylprolyl Isomerase D (PPID) (AA 85-115), (N-Term) antibodyPPID 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17211 unconjugated
anti-Peptidylprolyl Isomerase D (PPID) (AA 7-191) antibodyPPID 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Cyclophilin D antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Cyclophilin D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PPID (Peptidylprolyl Isomerase D (PPID))
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别名
- Cyclophilin D
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背景
- PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA- binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer, the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large- cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.
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UniProt
- Q08752
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途径
- Nuclear Hormone Receptor Binding
抗原
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