SCP2 抗体 (AA 33-547)
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Quick Overview for SCP2 抗体 (AA 33-547) (ABIN7874006)
抗原
See all SCP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-547
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原理
- SCP2 Antibody / Sterol carrier protein 2
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纯化方法
- Immunogen affinity purified
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免疫原
- E.coli-derived human SCP2 recombinant protein (Position: R33-L547) was used as the immunogen for the SCP2 antibody.
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亚型
- IgG
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anti-Sterol Carrier Protein 2 (SCP2) antibody
SCP2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Sterol Carrier Protein 2 (SCP2) (AA 1-143) antibodySCP2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2E9-1B3 unconjugated
anti-Sterol Carrier Protein 2 (SCP2) (AA 1-322) antibodySCP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sterol Carrier Protein 2 (SCP2) antibodySCP2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB790 unconjugated Recombinant Antibody
anti-Sterol Carrier Protein 2 (SCP2) (AA 358-385) antibodySCP2 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22648 unconjugated
anti-Sterol Carrier Protein 2 (SCP2) (AA 433-547) antibodySCP2 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sterol Carrier Protein 2 (SCP2) (AA 1-143) antibodySCP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sterol Carrier Protein 2 (SCP2) (AA 1-322) antibodySCP2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sterol Carrier Protein 2 (SCP2) antibodySCP2 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Carrier Protein 2 (SCP2) antibodySCP2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SCP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SCP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SCP2 (Sterol Carrier Protein 2 (SCP2))
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别名
- SCP2
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背景
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SCP2 antibody detects Sterol carrier protein 2, encoded by the SCP2 gene. Sterol carrier protein 2 is a non-specific lipid transfer protein involved in intracellular lipid metabolism, peroxisomal function, and cholesterol trafficking. SCP2 antibody provides researchers with a valuable reagent for studying lipid transport, peroxisomal disorders, and cholesterol regulation.
Sterol carrier protein 2 plays a critical role in binding and transferring a wide range of lipids, including cholesterol, fatty acids, and phospholipids. Research using SCP2 antibody has shown that it localizes to peroxisomes, mitochondria, and the cytosol, where it helps mediate transport between organelles. By facilitating lipid shuttling, SCP2 contributes to membrane biosynthesis, signaling, and energy metabolism.
Studies with SCP2 antibody have revealed that the protein is synthesized as a multifunctional peroxisomal enzyme complex containing both thiolase activity and lipid transfer function. This dual nature allows SCP2 to integrate fatty acid oxidation with lipid transport, making it essential for peroxisomal physiology. Loss of SCP2 activity disrupts cholesterol homeostasis and leads to peroxisome-related disease phenotypes.
Dysregulation of Sterol carrier protein 2 has been associated with metabolic disease, cancer, and neurodegeneration. Research using SCP2 antibody has shown that reduced expression alters cholesterol trafficking, contributing to lipid storage disorders. Elevated expression has been observed in tumors, where SCP2 enhances membrane biosynthesis and supports proliferation. These findings highlight its dual role in normal physiology and disease pathology.
SCP2 antibody is widely applied in immunohistochemistry, western blotting, and immunofluorescence. Immunohistochemistry demonstrates expression in liver, adrenal gland, and brain, western blotting quantifies levels in cell lines and tissues, immunofluorescence reveals localization to peroxisomes and cytoplasm. These methods make SCP2 antibody indispensable for lipid transport research.
By providing validated SCP2 antibody reagents, NSJ Bioreagents supports studies into lipid metabolism, peroxisomal disorders, and disease. Detection of Sterol carrier protein 2 provides researchers with insight into how lipid transfer proteins influence cellular function and pathology. -
UniProt
- P22307
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途径
- C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
抗原
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