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IL7R 抗体 (AA 33-433)

The 兔 多克隆 anti-IL7R antibody is suitable to detect IL7R in samples from 人. It has been validated for FACS, WB, ELISA 和 IHC (p).
产品编号 ABIN7874001
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL7R 抗体 (AA 33-433) (ABIN7874001)

抗原

See all IL7R 抗体
IL7R (Interleukin 7 Receptor (IL7R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL7R antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 33-433

    原理

    CD127 Antibody

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived human recombinant protein (amino acids A33-Q433) was used as the immunogen for the CD127 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CD127 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CD127 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    IL7R (Interleukin 7 Receptor (IL7R))

    别名

    CD127

    背景

    The interleukin-7 receptor, also known as IL7R alpha, is a protein found on the surface of cells. It is mapped to 5p13. Interleukin-7 receptor has been shown to play a critical role in the development of immune cells called lymphocytes - specifically in a process known as V(D)J recombination. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation. Knockout studies in mice suggest that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. Functional defects in this protein may be associated with the pathogenesis of severe combined immunodeficiency (SCID).

    UniProt

    P16871

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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