Cytokeratin 5 抗体 (AA 318-491)
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北京 101111
Quick Overview for Cytokeratin 5 抗体 (AA 318-491) (ABIN7873899)
抗原
See all Cytokeratin 5 (KRT5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 318-491
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原理
- Cytokeratin 5 Antibody / KRT5
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纯化方法
- Culture supernatant
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免疫原
- A recombinant human partial protein (amino acids 318-491) was used as the immunogen for this Cytokeratin 5 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the Cytokeratin 5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Culture supernatant with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cytokeratin 5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
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别名
- Cytokeratin 5
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背景
- This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium. Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express. Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.
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UniProt
- P13647
抗原
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