FOXO3 抗体 (AA 312-537)
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北京 101111
Quick Overview for FOXO3 抗体 (AA 312-537) (ABIN7873851)
抗原
See all FOXO3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 312-537
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原理
- FKHRL1 Antibody / FOXO3A
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R312-Q537) was used as the immunogen for the FKHRL1 antibody.
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亚型
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 471-673) antibodyFOXO3 适用: 人, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) antibodyFOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1E2 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the FKHRL1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FKHRL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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别名
- FKHRL1
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背景
- Forkhead box O3, also known as FKHRL1 (Forkhead in rhabdomyosarcoma-like 1) or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
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UniProt
- O43524
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
抗原
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