CST3 抗体 (AA 31-146)
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Quick Overview for CST3 抗体 (AA 31-146) (ABIN7873748)
抗原
See all CST3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 31-146
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原理
- Cystatin C Antibody / Cystatin 3
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纯化方法
- Purified
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免疫原
- Amino acids K31-A146 from the human protein were used as the immunogen for the Cystatin C antibody.
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亚型
- IgG2a
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应用备注
- Optimal dilution of the Cystatin C antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Cystatin C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CST3 (Cystatin C (CST3))
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别名
- Cystatin C
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背景
- Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
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UniProt
- P01034
抗原
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