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LRRC47 抗体 (AA 309-583)

This 兔 多克隆 antibody specifically detects LRRC47 in WB, ELISA 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7873742
发货至: 中国
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Quick Overview for LRRC47 抗体 (AA 309-583) (ABIN7873742)

抗原

LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

适用

  • 4
  • 3
  • 1

宿主

  • 4

克隆类型

  • 4
多克隆

标记

  • 4
This LRRC47 antibody is un-conjugated

应用范围

  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 1
    • 1
    • 1
    AA 309-583

    原理

    LRRC47 Antibody / Leucine-rich repeat-containing protein 47

    纯化方法

    Antigen affinity purified

    免疫原

    An E.coli-derived human recombinant protein (amino acids L309-R583) was used as the immunogen for the LRRC47 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the LRRC47 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the LRRC47 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

    别名

    LRRC47

    背景

    Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

    UniProt

    Q8N1G4
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