LRRC47 抗体 (AA 309-583) (Fluoro488)
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北京 101111
Quick Overview for LRRC47 抗体 (AA 309-583) (Fluoro488) (ABIN8005525)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 309-583
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原理
- Anti-LRRC47 Antibody Fluoro488 Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LRRC47 recombinant protein (Position: L309-R583).
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亚型
- IgG
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anti-Leucine Rich Repeat Containing 47 (LRRC47) (AA 533-583) antibody
LRRC47 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))
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别名
- LRRC47
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背景
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Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Gene Full Name: leucine rich repeat containing 47
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基因ID
- 57470
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UniProt
- Q8N1G4
抗原
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