Kallikrein 7 抗体 (AA 30-238)
Our Local Distributor
北京 101111
Quick Overview for Kallikrein 7 抗体 (AA 30-238) (ABIN7873578)
抗原
See all Kallikrein 7 (KLK7) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-238
-
原理
- Kallikrein 7 Antibody / Klk7
-
纯化方法
- Antigen affinity purified
-
免疫原
- An E.coli-derived rat recombinant protein (K30-N238) was used as the immunogen for the Kallikrein 7 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Kallikrein 7 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Kallikrein 7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Kallikrein 7 (KLK7)
-
别名
- Kallikrein 7
-
背景
- Kallikrein-related peptidase 7 (KLK7) is a serine protease that in humans is encoded by the KLK7 gene. KLK7 is a chymotrypsin-like serine protease of the member of peptidase S1 family. It is synthesized with a signal peptide of 22 amino acids (aa 1-22) and a propeptide region (aa 23-29) that are subsequently cleaved to generate the mature form. Human KLK7 displays about 40 to 60 % amino acid homology with other members of the family. It cleaves proteins with aromatic side chains in the P1 position. KLK7 is abundantly expressed in the skin and is also present in the brain, mammary gland, cerebellum, spinal cord, and kidney. Lower levels of expression have been reported in in salivary glands, uterus, thymus, thyroid, placenta, trachea, and testis. Its levels are shown to be up-regulated in ovarian carcinoma, especially late-stage serous carcinoma. Less differentiated tumors of more advanced stage show higher level KLK7 expression. KLK7 activity is inhibited by zinc and copper ions
-
UniProt
- P36373
-
途径
- Complement System
抗原
-