HGS 抗体 (AA 3-777)
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Quick Overview for HGS 抗体 (AA 3-777) (ABIN7873551)
抗原
See all HGS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-777
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原理
- HGS Antibody / HRS / HGF-regulated tyrosine kinase substrate
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids R3-D777) was used as the immunogen for the HGS antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the HGS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HGS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
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别名
- HGS
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背景
- Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.
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UniProt
- O14964
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途径
- EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation
抗原
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