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HGS 抗体 (Internal Region)

Name: HGS 抗体 (Internal Region)
SKU: ABIN6262232
Availability: OutOfStock

HGS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of HGS expression in Rat brain lysate (HGS 抗体 (Internal Region))

Western blot analysis on HepG2 cell lysate using HGS Antibody. (HGS 抗体 (Internal Region))

IF/ICC

ABIN6266695 at 1/100 staining human pancreas tissue sections by IHC-P. (HGS 抗体 (Internal Region))

IHC

4 images

产品编号 ABIN6262232

发货至: 中国

Datasheet as PDF

抗原 See all HGS 抗体

HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
抗原表位
8

4

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
45

31

21

3

2

1

1

1
人, 小鼠, 大鼠
宿主
39

5

1
兔
Compatible Secondaries
克隆类型
42

3
多克隆
标记
33

2

1

1

1

1

1

1

1

1

1

1
This HGS antibody is un-conjugated
应用范围
37

21

19

15

11

3

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

HGS Antibody detects endogenous levels of total HGS.

预测反应

Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human HGS, corresponding to a region within the internal amino acids.

亚型

IgG

Top Product

Discover our top product HGS Primary Antibody
anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 513-612) antibody
HGS 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 6D11 unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (C-Term) antibody
HGS 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (Internal Region) antibody
HGS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) antibody
HGS 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 513-612) antibody
HGS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (N-Term) antibody
HGS 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 301-350) antibody
HGS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (AA 548-777) antibody
HGS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) antibody
HGS 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 3H7 unconjugated

anti-Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS) (Center) antibody
HGS 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))

别名

HGS (HGS 产品)

别名

HRS antibody, Hrs antibody, fi34f05 antibody, zgc:63492 antibody, wu:fi34f05 antibody, Hgr antibody, ZFYVE8 antibody, CG2903 antibody, Dmel\\CG2903 antibody, HRS-2 antibody, Vps27 antibody, hrs antibody, l(2)23AB5 antibody, l(2)23Ad antibody, l(2)23Ad(Hrs) antibody, vps27 antibody, hgs antibody, hepatocyte growth factor-regulated tyrosine kinase substrate antibody, HGF-regulated tyrosine kinase substrate antibody, Hepatocyte growth factor regulated tyrosine kinase substrate antibody, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog antibody, HGS antibody, Hgs antibody, hgs antibody, Hrs antibody, hgs.L antibody

背景

Description: Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
Gene: HGS

分子量

86kDa

基因ID

9146

UniProt

O14964

途径

EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation