LIN28A 抗体 (AA 3-209)
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北京 101111
Quick Overview for LIN28A 抗体 (AA 3-209) (ABIN7873524)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 3-209
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原理
- LIN28A Antibody / Lin28
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids S3-N209) was used as the immunogen for the LIN28A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LIN28A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LIN28A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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别名
- LIN28A
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背景
- Protein lin-28 homolog A is a protein that in humans is encoded by the LIN28A gene. It is mapped to 1p36.11. This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
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UniProt
- Q9H9Z2
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途径
- Stem Cell Maintenance
抗原
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