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SERBP1 抗体 (AA 3-139)

The 小鼠 单克隆 anti-SERBP1 antibody is suitable to detect SERBP1 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7873491
发货至: 中国
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Room 801-803
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Quick Overview for SERBP1 抗体 (AA 3-139) (ABIN7873491)

抗原

See all SERBP1 抗体
SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

适用

  • 107
  • 32
  • 17
  • 8
  • 4
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  • 4
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  • 2
  • 2
  • 1
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宿主

  • 72
  • 34
小鼠

克隆类型

  • 70
  • 37
单克隆

标记

  • 69
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
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This SERBP1 antibody is un-conjugated

应用范围

  • 79
  • 43
  • 34
  • 29
  • 13
  • 13
  • 12
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SERBP1-3509
  • 抗原表位

    • 63
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 3-139

    原理

    SERBP1 Antibody / PAI-RBP1

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 3-139 from the human protein was used as the immunogen for the SERBP1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the SERBP1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))

    别名

    SERBP1

    背景

    SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.

    UniProt

    Q8NC51
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