SERBP1 抗体 (AA 3-139)
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北京 101111
Quick Overview for SERBP1 抗体 (AA 3-139) (ABIN7873491)
抗原
See all SERBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3-139
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原理
- SERBP1 Antibody / PAI-RBP1
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 3-139 from the human protein was used as the immunogen for the SERBP1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the SERBP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
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别名
- SERBP1
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背景
- SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.
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UniProt
- Q8NC51
抗原
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