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SERBP1 抗体 (AA 3-139)

SERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3493 unconjugated
产品编号 ABIN6939487
发货至: 中国
  • 抗原 See all SERBP1 抗体
    SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-139
    适用
    • 46
    • 27
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 31
    • 14
    小鼠
    克隆类型
    • 34
    • 12
    单克隆
    标记
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERBP1 antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 13
    • 13
    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
    克隆位点
    SERBP1-3493
    亚型
    IgG2b kappa
    Top Product
    Discover our top product SERBP1 Primary Antibody
  • 应用备注

    Positive Control: Human kidney or bladder tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
    别名
    SERBP1 (SERBP1 产品)
    别名
    CHD3IP antibody, HABP4L antibody, PAI-RBP1 antibody, PAIRBP1 antibody, 1200009K13Rik antibody, 9330147J08Rik antibody, AL022786 antibody, Pairbp1 antibody, Pai-Rbp1 antibody, Rda288 antibody, cgi-55 antibody, chd3ip antibody, habp4l antibody, pai-rbp1 antibody, pairbp1 antibody, rda288 antibody, hm:zeh0245 antibody, serbp1 antibody, wu:fa12d05 antibody, wu:fb36e07 antibody, wu:fc16f12 antibody, wu:fj13e12 antibody, zgc:55489 antibody, SERPINE1 mRNA binding protein 1 antibody, serpine1 mRNA binding protein 1 antibody, Serpine1 mRNA binding protein 1 antibody, SERPINE1 mRNA binding protein 1 L homeolog antibody, SERPINE1 mRNA binding protein 1a antibody, SERBP1 antibody, Serbp1 antibody, serbp1.L antibody, serbp1a antibody
    背景
    PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein), also known as SERBP1 (SERPINE1 mRNA-binding protein 1), CGI-55, CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein), HABP4L or PAI-RBP1, is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterone's antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer, suggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis.
    分子量
    60kDa
    基因ID
    26135
    UniProt
    Q8NC51
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