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CD276 抗体 (AA 7-3, AA 29-458)

The 兔 多克隆 anti-CD276 antibody is suitable to detect CD276 in samples from 人. It has been validated for WB, ELISA, FACS 和 IHC (p).
产品编号 ABIN7873425
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CD276 抗体 (AA 7-3, AA 29-458) (ABIN7873425)

抗原

See all CD276 抗体
CD276

适用

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宿主

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克隆类型

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多克隆

标记

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This CD276 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 7-3, AA 29-458

    原理

    B7-H3 Antibody / CD276

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids L29-Q458) was used as the immunogen for the B7-H3 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the B7-H3 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the B7-H3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CD276

    别名

    B7-H3

    背景

    Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the CD276 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    UniProt

    Q5ZPR3

    途径

    Cancer Immune Checkpoints
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