CD276 抗体 (AA 7-3, AA 29-458)
Our Local Distributor
北京 101111
Quick Overview for CD276 抗体 (AA 7-3, AA 29-458) (ABIN7873425)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 7-3, AA 29-458
-
原理
- B7-H3 Antibody / CD276
-
纯化方法
- Antigen affinity purified
-
免疫原
- E. coli-derived recombinant human protein (amino acids L29-Q458) was used as the immunogen for the B7-H3 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the B7-H3 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the B7-H3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- CD276
-
别名
- B7-H3
-
背景
- Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the CD276 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- Q5ZPR3
-
途径
- Cancer Immune Checkpoints
抗原
-