HDAC8 抗体 (AA 29-347)
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Quick Overview for HDAC8 抗体 (AA 29-347) (ABIN7873415)
抗原
See all HDAC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-347
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原理
- Histone Deacetylase 8 Antibody / HDAC8
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D29-E347) was used as the immunogen for the Histone Deacetylase 8 antibody.
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亚型
- IgG
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anti-Histone Deacetylase 8 (HDAC8) antibody
KO Validated HDAC8 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-377) antibodyHDAC8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyKD Validated HDAC8 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2495 unconjugated Recombinant Antibody
anti-Histone Deacetylase 8 (HDAC8) (AA 1-100) antibodyHDAC8 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (pSer39) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IF (cc), IHC (p) 宿主: 兔 Monoclonal 4C3 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (C-Term) antibodyHDAC8 适用: 人, 小鼠, 大鼠, 猴, Cow, 兔, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (N-Term) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-377) antibodyHDAC8 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyHDAC8 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6185 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the Histone Deacetylase 8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Histone Deacetylase 8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HDAC8 (Histone Deacetylase 8 (HDAC8))
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别名
- Histone Deacetylase 8
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背景
- HDAC8, Histone deacetylase 8, is an enzyme that in humans is encoded by the HDAC8 gene, and is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Sequence analysis predicted that the 377-amino acid HDAC8 protein contains the 9 conserved HDAC blocks that are presumably important for catalytic function. HDAC8 shares 54 % sequence similarity with HDAC1 and HDAC2 and 39 % similarity with HDAC3, making it a class I HDAC. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
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UniProt
- Q9BY41
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途径
- Cellular Glucan Metabolic Process
抗原
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