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MUS81 抗体 (AA 283-483)

This 兔 多克隆 antibody specifically detects MUS81 in ELISA 和 WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7873310
发货至: 中国
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Quick Overview for MUS81 抗体 (AA 283-483) (ABIN7873310)

抗原

See all MUS81 抗体
MUS81 (MUS81 Endonuclease Homolog (MUS81))

适用

  • 19
  • 7
  • 6
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 18
  • 1

克隆类型

  • 19
多克隆

标记

  • 15
  • 2
  • 1
  • 1
This MUS81 antibody is un-conjugated

应用范围

  • 12
  • 8
  • 5
  • 4
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 抗原表位

    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 283-483

    原理

    MUS81 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids H283-R483) was used as the immunogen for the MUS81 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the MUS81 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the MUS81 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MUS81 (MUS81 Endonuclease Homolog (MUS81))

    别名

    MUS81

    背景

    Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene. This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

    UniProt

    Q96NY9

    途径

    DNA Damage Repair
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