EPH Receptor B2 抗体 (AA 278-540)
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Quick Overview for EPH Receptor B2 抗体 (AA 278-540) (ABIN7873215)
抗原
See all EPH Receptor B2 (EPHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 278-540
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原理
- EPHB2 Antibody / Eph receptor B2
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids K278-K540) was used as the immunogen for the EPHB2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the EPHB2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the EPHB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EPH Receptor B2 (EPHB2)
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别名
- EPHB2
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背景
- Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. This gene is mapped to 1p36.12. This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
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UniProt
- P29323
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途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
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