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Mesothelin 抗体 (AA 273-407)

The 小鼠 单克隆 anti-Mesothelin antibody is suitable to detect Mesothelin in samples from 人, 小鼠 和 大鼠. It has been validated for IHC (p).
产品编号 ABIN7873191
发货至: 中国
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Room 801-803
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Quick Overview for Mesothelin 抗体 (AA 273-407) (ABIN7873191)

抗原

See all Mesothelin (MSLN) 抗体
Mesothelin (MSLN)

适用

  • 185
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人, 小鼠, 大鼠

宿主

  • 137
  • 68
  • 4
  • 3
  • 2
  • 1
小鼠

克隆类型

  • 123
  • 89
  • 3
单克隆

标记

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  • 18
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  • 1
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This Mesothelin antibody is un-conjugated

应用范围

  • 143
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MKPF-1
  • 抗原表位

    • 48
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    • 7
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    • 5
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    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 1
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    AA 273-407

    原理

    MSLN Antibody / Mesothelin

    纯化方法

    Protein G affinity

    免疫原

    A portion of amino acids 273-407 from the human protein was used as the immunogen for this MSLN antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the MSLN antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the MSLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Mesothelin (MSLN)

    别名

    MSLN

    背景

    Mesothelin is a 40 kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69 kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

    UniProt

    Q13421

    途径

    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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