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Mesothelin 抗体 (AA 273-407) (Biotin)

MSLN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal Biotin
产品编号 ABIN7126105
发货至: 中国
  • 抗原 See all Mesothelin (MSLN) 抗体
    Mesothelin (MSLN)
    抗原表位
    • 16
    • 9
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 273-407
    适用
    • 89
    • 24
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 76
    • 24
    • 4
    • 1
    • 1
    小鼠
    克隆类型
    • 74
    • 30
    • 2
    单克隆
    标记
    • 69
    • 11
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Mesothelin antibody is conjugated to Biotin
    应用范围
    • 68
    • 51
    • 24
    • 22
    • 12
    • 11
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Mesothelin is a 40 kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69 kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.
    交叉反应 (详细)
    Human, Mouse and Rat.
    纯化方法
    Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to Biotin.
    免疫原
    Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)
    亚型
    IgG2b
    Top Product
    Discover our top product MSLN Primary Antibody
  • 应用备注

    Positive Control: CAPAN-2 or HeLa cells. Lung Mesothelioma.

    Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    100 μg/mL
    缓冲液
    Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to Biotin. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    有效期
    24 months
  • 抗原
    Mesothelin (MSLN)
    别名
    MSLN (MSLN 产品)
    别名
    MPF antibody, SMRP antibody, MSLN antibody, mesothelin antibody, MSLN antibody, Msln antibody, LOC611363 antibody, LOC100524016 antibody
    背景
    CAK1, Megakaryocyte potentiating factor, Mesothelin, MSLN, SMR, SMRP,Mesothelin (Mesothelial Marker)
    Cellular localisation: Cell Surface and Secreted
    分子量
    40kDa (Mature form), 69kDa (Precursor)
    基因ID
    10232, 408488
    UniProt
    Q13421
    途径
    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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