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Recombinant Mesothelin 抗体 (AA 273-407)

The 小鼠 单克隆 anti-Mesothelin antibody is suitable to detect Mesothelin in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7873185
发货至: 中国
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Quick Overview for Recombinant Mesothelin 抗体 (AA 273-407) (ABIN7873185)

抗原

See all Mesothelin (MSLN) 抗体
Mesothelin (MSLN)

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Mesothelin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RMSLN-8764
  • 抗原表位

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    AA 273-407

    原理

    Recombinant MSLN Antibody / Mesothelin

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 273-407) from the human protein was used as the immunogen for the recombinant MSLN antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the recombinant MSLN antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant MSLN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Mesothelin (MSLN)

    别名

    MSLN

    背景

    Mesothelin is a 40 kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69 kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

    UniProt

    Q13421

    途径

    EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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