BMP4 抗体 (AA 27-279)
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Quick Overview for BMP4 抗体 (AA 27-279) (ABIN7873109)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-279
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原理
- Zebrafish Bmp2b Antibody / Bone morphogenetic protein 2
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Bmp2b recombinant protein (amino acids E27-D279) was used as the immunogen for the Zebrafish Bmp2b antibody.
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亚型
- Ig Fraction
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anti-Bone Morphogenetic Protein 4 (BMP4) antibody
BMP4 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (C-Term) antibodyBMP4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C11C7 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3C11H8 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 1-408) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 5-34) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 23-204) antibody (APC)BMP4 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 22-408) antibodyBMP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Bmp2b antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Bmp2b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- Bmp2b
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背景
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Bone morphogenetic protein 2b (Bmp2b) is a secreted signaling molecule belonging to the transforming growth factor-beta (TGF-beta) superfamily, and it plays a pivotal role in embryonic development, cell fate specification, and morphogenesis. In zebrafish (Danio rerio), Bmp2b is an essential factor in dorsoventral patterning, organogenesis, and skeletal development.
During early embryogenesis, bmp2b is expressed in ventral tissues and functions as a key morphogen that establishes dorsoventral polarity by forming a signaling gradient. Loss-of-function mutations in bmp2b, such as the well-known swirl mutant, result in dorsalized embryos, underscoring its essential role in ventral tissue specification. Bmp2b also regulates the development of multiple organ systems, including the heart, fins, and skeletal elements, through its influence on proliferation, differentiation, and apoptosis of progenitor cells.
Zebrafish Bmp2b is widely studied as a model for developmental signaling, stem cell biology, and tissue regeneration. It also provides a powerful system for investigating TGF-beta pathway modulation, signal transduction, and congenital malformations resulting from disrupted BMP signaling.
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UniProt
- O93369
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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