ULBP1 抗体 (AA 27-209)
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Quick Overview for ULBP1 抗体 (AA 27-209) (ABIN7873093)
抗原
See all ULBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-209
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原理
- ULBP1 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids W27-K209) was used as the immunogen for the ULBP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ULBP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ULBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ULBP1 (UL16 Binding Protein 1 (ULBP1))
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别名
- ULBP1
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背景
- UL16 binding protein 1 (ULBP1) is a cell surface glycoprotein encoded by ULBP1 gene located on the chromosome 6. The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9BZM6
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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