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IL-7 抗体 (AA 27-177)

The 小鼠 单克隆 anti-IL-7 antibody is suitable to detect IL-7 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7873089
发货至: 中国
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Room 801-803
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Quick Overview for IL-7 抗体 (AA 27-177) (ABIN7873089)

抗原

See all IL-7 (IL7) 抗体
IL-7 (IL7) (Interleukin 7 (IL7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-7 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

IL7-4269
  • 抗原表位

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    AA 27-177

    原理

    Interleukin-7 Antibody / IL-7 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 27-177) from the mature human protein was used as the immunogen for the Interleukin-7 antibody.

    亚型

    IgG2, kappa
  • 应用备注

    Optimal dilution of the Interleukin-7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Interleukin-7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-7 (IL7) (Interleukin 7 (IL7))

    别名

    Interleukin-7

    背景

    Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor gamma chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2), originally called 4PS.

    UniProt

    P13232

    途径

    JAK/STAT Signaling
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