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Recombinant IL-7 抗体 (AA 27-177)

This 兔 单克隆 antibody specifically detects IL-7 in FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7873088
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant IL-7 抗体 (AA 27-177) (ABIN7873088)

抗原

See all IL-7 (IL7) 抗体
IL-7 (IL7) (Interleukin 7 (IL7))

抗体类型

Recombinant Antibody

适用

  • 66
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  • 28
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  • 1
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宿主

  • 75
  • 26
  • 9
  • 3

克隆类型

  • 77
  • 36
单克隆

标记

  • 71
  • 14
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This IL-7 antibody is un-conjugated

应用范围

  • 83
  • 42
  • 31
  • 19
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  • 10
  • 10
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  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

IL7-7053R
  • 抗原表位

    • 15
    • 14
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
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    • 1
    AA 27-177

    原理

    Recombinant IL-7 Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 27-177) corresponding to the mature human IL7 protein was used as the immunogen for the recombinant IL-7 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant IL-7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant IL-7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-7 (IL7) (Interleukin 7 (IL7))

    别名

    IL-7

    背景

    Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor ? chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2), originally called 4PS.

    UniProt

    P13232

    途径

    JAK/STAT Signaling
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