IL-7 抗体 (AA 27-177)
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Quick Overview for IL-7 抗体 (AA 27-177) (ABIN7873083)
抗原
See all IL-7 (IL7) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 27-177
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原理
- IL-7 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 27-177 was used as the immunogen for the IL-7 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the IL-7 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL-7 (IL7) (Interleukin 7 (IL7))
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别名
- IL-7
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背景
- Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2), originally called 4PS.
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UniProt
- P13232
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途径
- JAK/STAT Signaling
抗原
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