GATA4 抗体 (AA 262-321)
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北京 101111
Quick Overview for GATA4 抗体 (AA 262-321) (ABIN7873033)
抗原
See all GATA4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 262-321
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原理
- GATA4 Antibody / GATA-binding factor 4 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 262-321) from the human protein was used as the immunogen for the GATA4 antibody.
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亚型
- IgG2b
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anti-GATA Binding Protein 4 (GATA4) (pSer262) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (pSer105) antibodyGATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) antibodyGATA4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 228-440) antibodyGATA4 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 50-150) antibodyGATA4 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 261-360) antibodyGATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 201-442) antibodyGATA4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 330-380) antibodyGATA4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 298-328), (C-Term) antibodyGATA4 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB13444 unconjugated
anti-GATA Binding Protein 4 (GATA4) (AA 296-442) antibodyGATA4 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated
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应用备注
- Optimal dilution of the GATA4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the GATA4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GATA4 (GATA Binding Protein 4 (GATA4))
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别名
- GATA4
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背景
- Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4, expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
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UniProt
- P43694
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途径
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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