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DNMT3B 抗体 (AA 258-472)

The 兔 多克隆 anti-DNMT3B antibody is suitable to detect DNMT3B in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN7872975
发货至: 中国
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Quick Overview for DNMT3B 抗体 (AA 258-472) (ABIN7872975)

抗原

See all DNMT3B 抗体
DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This DNMT3B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 258-472

    原理

    DNMT3b Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids M258-D472) was used as the immunogen for the DNMT3b antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DNMT3b antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the DNMT3b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

    别名

    DNMT3b

    背景

    DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

    UniProt

    Q9UBC3
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