GnRH2 抗体 (AA 25-86)
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Quick Overview for GnRH2 抗体 (AA 25-86) (ABIN7872895)
抗原
See all GnRH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-86
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原理
- Zebrafish Gnrh2 Antibody / Gonadotropin-releasing hormone 2 / Progonadoliberin
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Gnrh2 recombinant protein (amino acids Q25-K86) was used as the immunogen for the Zebrafish Gnrh2 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Gnrh2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Gnrh2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GnRH2 (Gonadotropin-Releasing Hormone 2 (GnRH2))
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别名
- Gnrh2
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背景
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Gonadotropin-releasing hormone 2 (Gnrh2) is a neuropeptide encoded by the gnrh2 gene in zebrafish (Danio rerio) and belongs to the conserved family of GnRH peptides that play essential roles in the regulation of reproductive physiology. Gnrh2 is primarily expressed in the midbrain tegmentum and is involved in modulating reproductive behavior, neuroendocrine signaling, and possibly feeding and locomotor activity.
Unlike Gnrh1, which is the main hypophysiotropic form regulating pituitary gonadotropin release, Gnrh2 is considered a non-hypophysiotropic GnRH variant and is thought to function in neuromodulation and reproductive behavior across vertebrates. In zebrafish, Gnrh2-expressing neurons have been implicated in the integration of sensory and hormonal signals, contributing to the fine-tuning of reproductive timing and behavior in response to environmental cues.
Due to its evolutionary conservation and tissue-specific expression, zebrafish Gnrh2 is a valuable model for studying neuroendocrine regulation, sexual behavior, and the functional diversification of GnRH isoforms.
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UniProt
- Q5Y835
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途径
- Hormone Activity
抗原
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