RNF8 抗体 (AA 243-485)
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Quick Overview for RNF8 抗体 (AA 243-485) (ABIN7872772)
抗原
See all RNF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 243-485
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原理
- RNF8 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Q243-F485) was used as the immunogen for the RNF8 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RNF8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RNF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RNF8 (Ring Finger Protein 8 (RNF8))
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别名
- RNF8
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背景
- E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants.
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UniProt
- O76064
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途径
- Production of Molecular Mediator of Immune Response
抗原
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