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Rubicon 抗体 (AA 241-271)

The 兔 多克隆 anti-Rubicon antibody (ABIN7872730) specifically detects Rubicon in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7872730
发货至: 中国
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Quick Overview for Rubicon 抗体 (AA 241-271) (ABIN7872730)

抗原

See all Rubicon (KIAA0226) 抗体
Rubicon (KIAA0226) (KIAA0226)

适用

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宿主

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克隆类型

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多克隆

标记

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This Rubicon antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 241-271

    原理

    Rubicon Antibody / RUBCN / BARON

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 241-271 from the human protein was used as the immunogen for the Rubicon antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Rubicon antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Rubicon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Rubicon (KIAA0226) (KIAA0226)

    别名

    Rubicon

    背景

    Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation. [UniProt]

    UniProt

    Q92622

    途径

    Autophagy
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