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CXCL12 抗体 (AA 24-99)

This 兔 多克隆 antibody specifically detects CXCL12 in IHC (p). It exhibits reactivity toward 斑马鱼.
产品编号 ABIN7872728
发货至: 中国
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Quick Overview for CXCL12 抗体 (AA 24-99) (ABIN7872728)

抗原

See all CXCL12 抗体
CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

适用

  • 86
  • 26
  • 14
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
斑马鱼

宿主

  • 80
  • 12
  • 10
  • 2
  • 1
  • 1

克隆类型

  • 73
  • 33
多克隆

标记

  • 59
  • 14
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
This CXCL12 antibody is un-conjugated

应用范围

  • 73
  • 38
  • 37
  • 24
  • 18
  • 12
  • 9
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 10
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-99

    原理

    Zebrafish Cxcl12 Antibody / Cxcl12a / Cxcl12b

    纯化方法

    Antigen affinity chromatography

    免疫原

    E. coli-derived zebrafish Cxcl12 recombinant protein (amino acids K24-V99) was used as the immunogen for the Zebrafish Cxcl12 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Cxcl12 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Cxcl12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

    别名

    Cxcl12

    背景

    Cxcl12, also known as stromal cell-derived factor 1, is a chemokine that plays a crucial role in the regulation of cell migration, particularly during embryonic development and immune cell trafficking. In zebrafish, Cxcl12 is essential for the proper guidance of various cell types, including primordial germ cells, neural crest cells, and hematopoietic stem cells.

    Cxcl12 signals through its receptor Cxcr4, and this signaling axis is conserved across vertebrates. In zebrafish embryos, Cxcl12 is expressed in defined tissue regions and acts as a chemoattractant, guiding migrating cells to their correct destinations. It is also involved in vascular development, organ positioning, and fin regeneration.

    Because of its conserved function and well-characterized roles in developmental and immune processes, zebrafish Cxcl12 is widely used as a model for studying chemokine signaling, stem cell migration, tumor metastasis, and inflammatory responses. It is also a valuable tool in regenerative biology and drug discovery targeting chemokine pathways.

    UniProt

    Q8AV10

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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