STRADB 抗体 (AA 24-411)
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Quick Overview for STRADB 抗体 (AA 24-411) (ABIN7872690)
抗原
See all STRADB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-411
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原理
- ILPIP Antibody / Als2Cr2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids E24-E411) was used as the immunogen for the ILPIP antibody.
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亚型
- IgG
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anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 319-418) antibody
STRADB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (C-Term) antibodyVerified STRADB 适用: 人 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 212-418) antibodySTRADB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 251-350) antibodySTRADB 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 1-95) antibodySTRADB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 200-250) antibodySTRADB 适用: 人, Cow, 犬, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (AA 274-303), (C-Term) antibodySTRADB 适用: 人 WB 宿主: 兔 Polyclonal RB15723 unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (Intermediate Domain) antibodySTRADB 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor beta (STRADB) (C-Term) antibodySTRADB 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ILPIP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ILPIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- STRADB (STE20-Related Kinase Adaptor beta (STRADB))
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别名
- ILPIP
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背景
- STE20-related kinase adapter protein beta, also called ILP-interacting protein (ILPIP) and Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein (Als2Cr2), is an enzyme that in humans is encoded by the STRADB gene. This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9C0K7
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途径
- AMPK Signaling
抗原
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