LHB 抗体 (AA 24-140)
Our Local Distributor
北京 101111
Quick Overview for LHB 抗体 (AA 24-140) (ABIN7872666)
抗原
See all LHB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 24-140
-
原理
- Zebrafish Luteinizing hormone beta Antibody / Lhb
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- E. coli-derived zebrafish Luteinizing hormone beta recombinant protein (amino acids L24-Y140) was used as the immunogen for the Zebrafish Luteinizing hormone beta antibody.
-
亚型
- Ig Fraction
-
-
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 21-141) antibody
LHB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 23-141) antibodyLHB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) antibodyLHB 适用: 人 IHC 宿主: 小鼠 Monoclonal LHb-1214 unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 21-141) antibodyLHB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 78-104), (C-Term) antibodyLHB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14582 unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (AA 21-141) antibodyLHB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) (Internal Region) antibodyLHB 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone beta Polypeptide (LHB) antibodyLHB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the Zebrafish Luteinizing hormone beta antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Zebrafish Luteinizing hormone beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- LHB (Luteinizing Hormone beta Polypeptide (LHB))
-
别名
- Luteinizing hormone beta
-
物质类
- Hormone
-
背景
-
Luteinizing hormone (LH) is a glycoprotein hormone critical for the regulation of reproductive function in vertebrates. It consists of a common alpha subunit and a hormone-specific beta subunit, the latter conferring biological specificity. In zebrafish (Danio rerio), the Lhb gene encodes the beta subunit of LH and plays a key role in the hypothalamic-pituitary-gonadal (HPG) axis.
Zebrafish Lhb is produced by gonadotrope cells in the anterior pituitary and is essential for triggering final oocyte maturation and ovulation in females, as well as steroidogenesis and spermatogenesis in males. Its expression is tightly regulated by gonadotropin-releasing hormone (GnRH) and modulated by sex steroids through feedback mechanisms.
The zebrafish model has been instrumental in dissecting the molecular and developmental regulation of lhb expression. Notably, Lhb mRNA becomes detectable during larval stages and increases during sexual maturation. Functional studies using gene knockout and reporter lines have demonstrated that Lhb is indispensable for fertility, and its disruption results in reproductive failure.
Due to its conserved structure and function, zebrafish Lhb serves as a valuable model for studying reproductive endocrinology, pituitary cell differentiation, and hormone signaling pathways in vertebrates.
-
UniProt
- Q6TCF5
-
途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
抗原
-
